2011 Pharmacist Practice Exam - Pharmaceutical Chemistry Other Antibiotics
- Categories:Industry News
- Author:
- Origin:
- Time of issue:2018-02-27 15:34
- Views:
(Summary description)
(A) Chloramphenicol action and adverse reactions, stability
Chloramphenicol is a broad-spectrum antibiotic, the main disadvantages are high toxicity, inhibition of the bone marrow hematopoietic system, causing aplastic anemia, so the clinical application is limited. However, it is still one of the preferred drugs in controlling typhoid and typhus. Its aqueous solution is prone to hydrolysis reaction of amide in the range of pH2-7, and the degradation speed is accelerated with the increase of temperature.
(B) The main pharmacological effects of peptide antibiotics polymyxin and cyclosporine A
(C) The effect of lincomycin
Lincomycin, which is effective against gram-positive bacteria and has strong penetration to tissues, is therefore suitable for osteomyelitis. It is also used to treat staphylococci, hemolytic streptococci, pneumococci causing skin and soft tissue infections, upper and lower respiratory tract infections, etc.
2011 Pharmacist Practice Exam - Pharmaceutical Chemistry Other Antibiotics
(Summary description)
(A) Chloramphenicol action and adverse reactions, stability
Chloramphenicol is a broad-spectrum antibiotic, the main disadvantages are high toxicity, inhibition of the bone marrow hematopoietic system, causing aplastic anemia, so the clinical application is limited. However, it is still one of the preferred drugs in controlling typhoid and typhus. Its aqueous solution is prone to hydrolysis reaction of amide in the range of pH2-7, and the degradation speed is accelerated with the increase of temperature.
(B) The main pharmacological effects of peptide antibiotics polymyxin and cyclosporine A
(C) The effect of lincomycin
Lincomycin, which is effective against gram-positive bacteria and has strong penetration to tissues, is therefore suitable for osteomyelitis. It is also used to treat staphylococci, hemolytic streptococci, pneumococci causing skin and soft tissue infections, upper and lower respiratory tract infections, etc.
- Categories:Industry News
- Author:
- Origin:
- Time of issue:2018-02-27 15:34
- Views:
(A) Chloramphenicol action and adverse reactions, stability
Chloramphenicol is a broad-spectrum antibiotic, the main disadvantages are high toxicity, inhibition of the bone marrow hematopoietic system, causing aplastic anemia, so the clinical application is limited. However, it is still one of the preferred drugs in controlling typhoid and typhus. Its aqueous solution is prone to hydrolysis reaction of amide in the range of pH2-7, and the degradation speed is accelerated with the increase of temperature.
(B) The main pharmacological effects of peptide antibiotics polymyxin and cyclosporine A
(C) The effect of lincomycin
Lincomycin, which is effective against gram-positive bacteria and has strong penetration to tissues, is therefore suitable for osteomyelitis. It is also used to treat staphylococci, hemolytic streptococci, pneumococci causing skin and soft tissue infections, upper and lower respiratory tract infections, etc.
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